How Much Milk Thistle Per Day On Cycle?

The anti-inflammatory, antibacterial, and CNS properties of milk thistle have all been studied. It’s been researched for allergic rhinitis, asthma, cancer treatment-related side effects, rheumatoid arthritis, type 2 diabetes, drug-induced hepatotoxicity, drug-induced nephrotoxicity, dyslipidemia, and thalassemia, but there aren’t enough clinical trials to back up these claims. The most prevalent application of milk thistle is for the treatment of liver illnesses (alcohol-induced and viral hepatitis), but the majority of clinical research have yielded mixed outcomes.


Milk thistle is considered safe when taken orally in divided doses for up to 41 months at a level of 420 mg/day. For dyspepsia and biliary system illnesses, one source recommends daily doses of 12 to 15 g of dried fruits, while an extract containing 200 to 400 mg/day of silymarin is thought to be beneficial in a variety of liver disorders.


Patients who are allergic to any plant in the Asteraceae family should avoid milk thistle. Due to the extract’s suspected estrogenic effects, avoid using the aboveground sections of the plant in women with hormone-sensitive disorders (eg, breast, uterine, and ovarian malignancies; endometriosis; uterine fibroids) unless under the guidance of a physician. The estrogenic effects of the more regularly used milk thistle seed extracts remain unknown.


Milk thistle has been utilized in pregnancy for centuries. Limited clinical investigations in pregnant women show that it is safe to use; nevertheless, further evidence is needed to validate safety. Women who are pregnant or breastfeeding should exercise caution.


Milk thistle has been shown to have inhibitory or inductive activity on cytochrome P450 (CYP-450) 1A2, 2C19, 2D6, 2E1, and 3A4, as well as P-glycoprotein, according to inconsistent evidence. When medications processed by these enzymes are given at the same time as milk thistle, careful monitoring is required.

Adverse Reactions

Silymarin is well tolerated; the most common side effects following oral administration were minor gastrointestinal problems (eg, abdominal bloating, abdominal fullness or pain, anorexia, changes in bowel habits, diarrhea, dyspepsia, flatulence, nausea). There have also been reports of headaches and itching.


Clinically, silymarin has no toxic effects at doses of 1,200 mg/day; however, doses greater than 1,500 mg/day have been documented to cause mild allergies.

How much milk thistle can you take a day?

For example, milk thistle supplements are tolerated at doses of up to 700 mg three times each day for 24 weeks ( 1 ). Stomach trouble, nausea, and diarrhea are all possible side effects of the herb ( 1 ).

Should I take milk thistle while on steroids?

When milk thistle is combined with steroids, the silymarin protects the liver and helps to rebuild damaged cells. The capacity of milk thistle to stimulate the liver to cleanse itself of toxins has also been discovered to be beneficial.

Is milk thistle 1000 mg too much?

Milk thistle supplements are most usually sold as capsules, but they can also be found as tablets, tea bags, or oral tinctures. The dosages vary from 175 to 1,000 mg. In general, the bigger the dose, the higher the chance of adverse consequences.

Can you have too much milk thistle?

When consumed by oral, milk thistle is usually regarded as safe ( 1 , 45 ). In fact, only approximately 1% of persons reported negative effects in studies when large doses were administered for lengthy periods of time ( 1 ). When milk thistle side effects are observed, they are typically stomach disturbances such as diarrhea, nausea, or bloating.

Is it OK to take milk thistle every day?

In general, taking milk thistle in approved amounts is safe. Nausea, flatulence, diarrhea, and a loss of appetite have all been reported by some persons. Others have complained of headaches or itching after taking it.

Milk thistle can trigger allergic reactions in those who are allergic to other plants in the same family. Ragweed, daisies, marigolds, and chrysanthemums are examples.

People with diabetes should see their doctor before taking milk thistle because it has the potential to reduce blood sugar levels.

If you have breast, uterine, or ovarian cancer, endometriosis, or uterine fibroids, don’t take it. It has the ability to imitate estrogen. Before taking milk thistle or any other herbal supplement, consult your doctor if you are pregnant or breastfeeding.

Does milk thistle really cleanse the liver?

The milk thistle is a prickly shrub that can reach a height of 10 feet. The plant is a California native. Milk thistle, on the other hand, thrives in similar climates all over the world. The milk-like liquid released when the leaves are crushed gives the plant its name. The plant produces a stunning pink flower bulb. Breastfeeding mothers, persons with digestion problems, and people looking for skin treatments are all people who utilize milk thistle.

The hidden power of thistle

Teas, oils, and powders can be made from any part of the plant. The silymarin extract, on the other hand, may be the most effective component. When the blossoms are dry, they each generate multiple seeds. People have been able to extract the chemical silymarin from the seeds by grinding them. Silymarin is a flavonoid with anti-inflammatory, antioxidant, and therapeutic properties. The substantial link between silymarin and liver cells has been discovered by researchers.

Impacting the liver

The liver is the body’s largest internal organ and the purifier of blood. Humans rely significantly on this crucial organ for everything from absorbing nutrients to detoxifying the body. Everything you eat goes via your liver. Alcohol, prescription medicines, pesticides, processed foods, and heavy metals found in water are all examples of this. Because of these reasons, the liver has to work harder than ever before. The antioxidant capabilities of milk thistle protect the liver in a variety of ways.

Detoxifying the liver

The liver has two stages of detoxification. The first stage converts passing enzymes into free radicals. Glutathione, an antioxidant, then binds to the free radicals. This aids the body’s natural removal of harmful substances. Silymarin aids in glutathione regeneration and maintenance. This, in turn, aids liver detoxification.

Disease treatment and prevention

Liver damage has been connected to diseases such as hepatitis, psoriasis, and jaundice. Studies have shown that a silymarin extract can help treat hepatitis C. However, without proper treatment, the liver can develop fatty liver disease, cirrhosis, and liver failure. Silymarin aids protein synthesis while also forming a protective barrier on cells to shield them from further harm. Pre-treatment with silymarin, according to another study, reduced liver damage caused by a variety of hazardous chemicals.

Liver healing and regeneration

Milk thistle protects the liver from oxidative stress and free radical damage. Milk thistle has been shown in studies to help repair damaged cells. Silymarin also helps to protect the liver from the effects of alcohol and some prescription medications. Many individuals assume that the liver detoxes itself and doesn’t require any assistance. While this is a compelling argument, if the liver is not properly cared for, it will continue to incur harm.

Care for your liver today

To protect and detox the liver, consider taking a high-potency milk thistle extract. This wonderful natural herb aids in the maintenance of liver health in young people. After the age of 40, the liver’s cleansing power begins to wane. Milk thistle can help with both prevention and repair, regardless of age. A healthy liver isn’t just about having good blood. The spleen, gastric, and endocrine systems all benefit as well. To detox the liver, consult a pharmacist or doctor for the proper milk thistle dosage.

Can milk thistle reverse liver damage?

Milk thistle will neither heal or reverse existing liver damage, nor will it treat hepatitis B or C virus infection. People with cirrhosis issues should avoid taking milk thistle (such as variceal bleeding or ascites).

How much milk thistle should I take daily for fatty liver?

Milk thistle (Silybum marianum) is a liver-healing herb native to Europe, Asia Minor, and Northern Africa. Multiple flavanolignans, collectively known as silymarin, are found in milk thistle seed extracts, primarily silybinin, silychristin, and silydianin. Silymarin has been proven in cell culture and animal models to prevent or mitigate acute liver injury caused by a variety of toxins, including acetaminophen and Amanita phalloides. Human trials on silymarin in chronic liver disease patients have been promising yet equivocal. In controlled trials in chronic hepatitis C and nonalcoholic fatty liver disease, silymarin showed little or no efficacy in reducing disease activity or decreasing disease progression. Milk thistle is sold as capsules or tablets containing 250 to 750 mg of ethanol extracted silymarin. It is said to help with liver disease, notably alcoholic and viral liver disease. The daily dosage varies, but it is usually taken two to three times per day. In Europe, pure silybinin intravenous formulations are licensed for the treatment of Amanita phalloides mushroom poisoning. There have been no published prospective controlled trials of intravenous silybinin. Oral silymarin has minimal, if any, negative side effects and is well tolerated at high daily doses.

Should I take milk thistle in the morning or night?

Our oil is made from the plant’s seeds, which are cold-pressed. It has a somewhat different nutrient profile, making it great for detoxifying your body while also caring for your skin and heart.

Our oil is high in vitamin E, a potent antioxidant that helps the body combat oxidative stress. It also contains omega-6 fatty acids, which are beneficial to the body when obtained from vegetable sources.

It has a wonderful, light, and nutty flavor that makes it ideal for salad dressings, soups, and dips where the flavor can truly shine.

This could be a wonderful alternative for you if you frequently eat Mediterranean and Middle Eastern foods, which frequently use flavored oils in drizzles and dips.

When to take milk thistle oil, and how long to take it for

You can take milk thistle oil at any time of day because it is well accepted by your body. It won’t keep you awake at night, and you can take it even if you’re hungry.

We advocate incorporating it into your meals because it has a pleasant flavor and goes well with other flavors like almonds and vegan cheese.

Consider it more of a culinary component than a supplement; it’ll still provide you with a slew of health benefits without requiring you to consume pure oil (unless you want to!).

Drizzle a small amount over salads or drips in the same way you would olive oil. One spoonful of milk thistle oil per day is recommended.

If you’re using prescription medicine, such as birth control, talk to your doctor before incorporating it into your routine, as there may be an interaction.

It’s also recommended to avoid it while nursing and pregnancy, as there hasn’t been much research done on its use at these times.

Can you take milk thistle every day?

Yes, most people tolerate it well and it is typically regarded a safe addition to your diet.

Because your body may take some time to adjust, start with a tiny dose and gradually increase to our advised quantity.

There isn’t a specific time of day when you should take it, so we recommend focusing on the things you think it will go well with. It can be consumed with or without meals.

Having a bowl of nutty porridge first thing in the morning? Its flavors will be enhanced by a dash of milk thistle oil. For lunch, how about pasta? Swap your olive oil for a sprinkle of milk thistle as a finishing touch, as the Italians do.

It’s crucial to keep in mind that milk thistle is a potent herb. It is the subject of substantial investigation for therapeutic purposes. In other words, it’s not an overlooked substance in your body!

Listen to your body and experiment with amounts until you discover the one that’s suitable for you, just like you would with any other food. You can take it every day or use it as a seasoning in your favorite foods every now and then.

Whatever method works best for you, your body will get the advantages of this wonderful plant in no time.